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Nano Spray Drying in Laboratory Scale

Fine Particles from Small Sample Quantities

Jul. 23, 2010
Fig. 2: SEM pictures of spray dried trehalose particles (from left to right): 1 % trehalose spray dried with 7.0 µm spray mesh; 1 % trehalose spray dried with 4.0 µm spray mesh; 0.1 % trehalose spray dried with 4.0 µm mesh
Fig. 2: SEM pictures of spray dried trehalose particles (from left to right): 1 % trehalose spray ... more
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Especially for pharmaceutical applications a homogenous size distribution of particles is of enormous importance. For a controllable drug release behavior and an efficient delivery to the target cells the agent particles must have a nearly identical particle size and shape. An appropriate method to achieve small particles with a homogenous size is spray drying. Traditional spray dryers are instruments for production scales and need large volumes which are often not available in R&D laboratories.

Authors:
Dr. Cordin Arpagaus, Büchi Labortechnik (corresponding author)
Prof. Dr. Wolfgang Friess, Ludwig-Maximilians-University
Katja Schmid, Ludwig-Maximilians-University

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Keywords : Analytik Büchi Laboratory Nanoparticle Nanospray Particles Pharma Physics R&D Sample Spray Dryer

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