25.01.2012

Qiagen to Provide siRNA Libraries in Labcyte Acoustically Compatible Microplates

Qiagen and Labcyte, the developer of acoustic liquid handling, announced that Qiagen FlexiPlate siRNA reagent libraries are now available in Labcyte Echo qualified microplates. These microplates enable researchers to use the Echo liquid handler to miniaturize the transfer of small interfering RNA reagents. more08.11.2011

Flow Cytometry Immune Monitoring

Beckman Coulter now offers Streptamer technology, providing a novel method for the isolation and characterization of functional antigen-specific T-cells by fluorescence-activated or magnet-assisted cell sorting. Streptamer technology, manufactured by IBA, includes Ag-specific multimers available in a number of human alleles and mouse models and attached to either magnetic beads or fluorescently labeled Strep-Tactin. more04.10.2011

New Method for Single Cell Analysis Measures DNA Topoisomerase Activity

A collaboration between Danish and American researchers has resulted in the development of a new method that enables the measurement of enzyme activities in individual human cells. This method can be used to measure how cell-to-cell variation in tumors affects the overall response to chemotherapy and thus clarify some of the molecular causes of the chemo-resistance often seen in cancer patients. In the long run, the researchers hope that the method can be used to target chemotherapy to those patients who benefit from this treatment. more28.09.2011

NIBRT and GE Healthcare Life Sciences Collaborate

The National Institute for Bioprocessing Research and Training (NIBRT), Ireland and GE Healthcare Life Sciences announced a joint research collaboration to drive advances in technologies for the development and functional analysis of therapeutic antibodies, protein-based drugs that are increasingly used to treat diseases such as cancer, rheumatoid arthritis and multiple sclerosis. more15.09.2011

Brand's New Strip Plates for Immunological Application

A critical component for the high specificity and selectivity of ELISA testing is the effective binding of antigens or antibodies to the surface of the microplates. With the new strip plates for immunological applications Brand significantly extends the wide range of Brandplates microplates. These 96-well strip plates 12 x F8 have ideal optical characteristics and are manufactured according to ANSI/SBS standards. more22.08.2011

Innate Immune Assay for the Examination of Receptor Activity

Pattern recognition receptors (PRRs) are the first defense line of the innate immune system. In the last years PRRs had been studied in different ways resulting in a lot of new insights. However, it was not possible to investigate individual combinations of PRRs and their specific ligands because of the complex network in immune signaling. A cell-based assay developed at Fraunhofer IGB allows a direct way to detect the activity of individual human PRR-receptors in a highly specific way. more18.07.2011

Miniaturization of Cell Based Assays- Part 1: Problems and Solutions

The last decade has seen a year on year increase in the production and testing of new biologically active compounds against a rapidly growing portfolio of potential therapeutic targets. This elevated research and development activity has arisen as a direct result of the completion of the human genome-sequencing project accompanied with advances in chemical synthesis and drug design. more05.07.2011

LGC Acquires KBioscience

LGC, an international science-based company and market leader in analytical, forensic and diagnostic services and reference standards, announce that LGC's Genomics division and KBioscience have come together to create a market-leading genomic services and solutions provider. more25.05.2011

Mutation Profiling by Qiagen's qBiomarker Somatic Mutation PCR Array System

Qiagen launches the qBiomarker Somatic Mutation PCR Array System, designed for rapid and accurate mutation profiling in basic research and drug discovery. The assays consist of collections of pathway or cancer-specific assays in 96- or 384-well plate formats with a number of pathways (EGFR, ErbB2, etc.) and cancer types. more16.05.2011

Microscale Thermophoresis: Drug-screening Assay Based on GPCRs

Receptor proteins located within the cell membrane serve to convey molecules or information into the interior. Because numerous drugs function by binding to such receptors, their interactions play important roles in the fight against various diseases. For example, the coupling can activate a signal chain which in the end specifically changes the metabolism of malignant cells. more