Gene Silencing
02.02.2011
The biopharmaceutical company Antisense Pharma announced that the South Korean health agency KFDA as well as the Taiwanese health agency TFDA have granted their approvals for the implementation of clinical studies using the anti-cancer drug trabedersen for patients with high-grade brain tumors. Trabedersen is a gene-silencing substance inhibiting the tumor factor Transforming Growth Factor beta 2 (TGF-β2) at its translational level. The efficacy and tolerability of trabedersen for high-grade glioma has already been demonstrated during a randomized and actively controlled Phase IIb study.
more02.09.2010
Sigma Life Science, the innovative biological products and research services business of Sigma-Aldrich announced the global release of a range of engineered mammalian cell lines. This new product range combines Sigma's proprietary CompoZr zinc finger nuclease (ZFN) technology with the Company's extensive experience in gene silencing, to offer innovative tools for drug discovery, compound screening and fundamental research applications.
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