16.03.2012
"Coffee: Emerging Health Benefits and Disease Prevention" is a book that gives an overview of the recent scientific advances in this field.
more27.09.2011
Biotie Therapies and Newron Pharmaceuticals announced that they have signed an agreement for Biotie to acquire Newron in a transaction valued at EUR 45 million (the "Transaction"). The Transaction is still subject inter alia to the approval by the EGM of Newron expected to be convened at the end of October 2011.
In acquiring Newron Biotie creates:
more05.09.2011
Scientists from Heptares Therapeutics have used Diamond Light Source, the UK's national synchrotron facility, to understand the structure of a protein involved in Parkinson's disease and other neurological disorders. Their findings, published in the journal Structure, could pave the way for a new generation of targeted drug treatments.
more20.01.2011
Domain Therapeutics announced that an exclusive development and licensing agreement with Merck Serono, a division of Merck KGaA, Darmstadt, Germany, was signed to develop metabotropic glutamate receptor 4 (mGluR4) Positive Allosteric Modulator (PAM) drugs targeting Parkinson's disease and other neurodegenerative diseases.
more19.01.2011
Neurodegenerative diseases such as Alzheimer's, Huntington's chorea or Parkinson's often are developed due to protein aggregation. Scientists at the Max Planck Institute of Biochemistry (MPIB) in Martinsried near Munich, Germany, now discovered a fundamental mechanism which explains how toxic protein aggregation occurs and why it leads to a widespread impairment of essential cellular functions. "Not all proteins are affected by aggregation", says Heidi Olzscha, PhD student at the MPIB.
more07.01.2011
Thomas Kodadek and his colleagues from the Florida campus of The Scripps Research Institute, have developed a novel technology that is able to detect the presence of immune molecules specific to Alzheimer's disease in patients' blood samples. While still preliminary, the findings offer clear proof that this breakthrough technology could be used in the development of biomarkers for a range of human diseases.
more02.11.2010
Researchers at Karolinska Institutet have shown that they may be able to monitor the aging process in the brain, by using MRI technique to measure the brain lactic acid levels. Their findings suggest that the lactate levels increase in advance of other aging symptoms, and therefore could be used as an indicator of aging and age-related diseases of the CNS.
more11.10.2010
CeGaT, Center for Genomics and Transcriptomics, announced that it is offering Sure Select Enrichment and SOLiD System sequencing-based genetic screening for hereditary eye diseases, epilepsy, metabolic and neurodegenerative disorders. Currently available panels include genes associated with Parkinson, ALS, dementia, non-syndromic and syndromic epilepsy, metabolic disorders and genes associated with hereditary eye diseases.
http://www.cegat.de
more02.09.2010
One of the leading scientists of our age - American Nobel Prize laureate Paul Greengard - is to be awarded the Karolinska Institutet Gold Medal, which is being given during the year of the university's 200-year anniversary. Dr. Greengard receives the medal for his research, which has increased our understanding of neurological and mental diseases, and for his more than 40 years of collaboration with Karolinska Institutet.
more01.07.2010
An increasingly aging population will add to the number of individuals suffering from amyloid. Protein Misfolding Diseases provides a systematic overview of the current and emerging therapies for these types of protein misfolding diseases, including Alzheimer's, Parkinson's, and Mad Cow. The book emphasizes therapeutics in an amyloid disease context to help students, faculty, scientific researchers, and doctors working with protein misfolding diseases bridge the gap between basic science and pharmaceutical applications to protein misfolding disease.
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