A tiny fruit fly's retina may hold the key to understanding the cause of the progression of Alzheimer's disease, according to a newly published study by researchers at the University of Dayton and the University of Florida.
Amit Singh, assistant professor of biology, worked with University of Dayton collaborator Madhuri Kango-Singh, pre-med students, graduate students and researchers at the University of Florida to investigate early detection of Alzheimer's, an incurable disease that afflicts an estimated 5.4 million Americans.
Using the fruit fly's eye as a model, the research team discovered that memory loss can likely be prevented by blocking the death of cells through the manipulation of a key gene. Their research is published in PLoS ONE, an international, peer-reviewed online journal.
Read more within the original publication:
Meghana Tare, Rohan M. Modi, Jaison J. Nainaparampil, Oorvashi Roy Puli, Shimpi Bedi, Pedro Fernandez-Funez, Madhuri Kango-Singh, Amit Singh: Activation of JNK Signaling Mediates Amyloid-ß-Dependent Cell Death. PLoS One. 2011;6(9):e24361. Epub 2011 Sep 14.
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Keywords : Alzheimer Amit Singh Drosophila Jaison J. Nainaparampil Madhuri Kango-Singh Meghana Tare Oorvashi Roy Puli Pedro Fernandez-Funez PLos One Rohan M. Modi Shimpi Bedi University of Dayton University of Florida
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