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Neurobiology: Bridging the Gap

Oct. 21, 2011
Top image: Magnetic resonance images comparing a healthy subject (left) with an AgCC patient (right). The corpus callosum is the thick, 'c'-shaped structure outlined in the healthy brain and missing from the AgCC brain. Bottom image: Functional magnetic resonance images highlight symmetric patterns of synchronized activity in both healthy (left) and AgCC subjects (right) during rest with eyes closed. More than 15 of this type of network were found to be preserved in AgCC subjects. Credit: California Institute of Technology
Top image: Magnetic resonance images comparing a healthy subject (left) with an AgCC patient ... more

Caltech neuroscientists find normal brain communication in people who lack connections between right and left hemispheres.

Like a bridge that spans a river to connect two major metropolises, the corpus callosum is the main conduit for information flowing between the left and right hemispheres of our brains. Now, neuroscientists at the California Institute of Technology (Caltech) have found that people who are born without that link-a condition called agenesis of the corpus callosum, or AgCC-still show remarkably normal communication across the gap between the two halves of their brains.

Their findings are outlined in a paper published October 19 in The Journal of Neuroscience.

Read more within the original publication:
J. Michael Tyszka, Daniel P. Kennedy, Ralph Adolphs, and Lynn K. Paul: Intact Bilateral Resting-State Networks in the Absence of the Corpus Callosum. The Journal of Neuroscience, 19 October 2011, 31(42): 15154-15162; doi: 10.1523/​JNEUROSCI.1453-11.2011

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Keywords : California Institute of Technology Caltech Daniel P. Kennedy J. Michael Tyszka Journal of Neuroscience Lynn K. Paul Neurobiology Ralph Adolphs

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