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Beckman Coulter now offers Streptamer technology, providing a novel method for the isolation and characterization of functional antigen-specific T-cells by fluorescence-activated or magnet-assisted cell sorting. Streptamer technology, manufactured by IBA, includes Ag-specific multimers available in a number of human alleles and mouse models and attached to either magnetic beads or fluorescently labeled Strep-Tactin. The addition of the technology to Beckman Coulter's Itag MHC Tetramer and Itopia Immune Monitoring product lines provides researchers with a comprehensive range of methods for sorting and characterizing cells.
Combined with current Tetramer and Itopia reagents, the technology allows researchers to expand their use of tetramers to include in vivo experimentation. The reversible, antigen-specific staining of T-cells enabled by Streptamers leaves the isolated T-cells phenotypically and functionally indistinguishable from untreated cells.
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Keywords : Assay Beckman Coulter Cell Sorting Flow cytometry Fluorescence Streptamer Technology
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