Laboratory Journal – Business Web for Users in Science and Industry en Special Review Issue of "Advanced Science" Online! To celebrate their constant high impact factor, our colleagues from Advanced Science have published a special issue.  To put it in their words: "In this issue we have once again compiled a variety of overview articles that demonstrate the broad range of topics covered in the journal: From polymer science to robotics, from computer simulations of supercapacitors to photodynamic therapy, from batteries to aggregation-induced emission – Advanced Science has it all." Wed, 16 Aug 2017 10:40:00 +0000 Hitachi`s Fluorescence Spectrophotometer F-7100 Hitachi has released the new fluorescence spectrophotometer F-7100 which provides "best-in-class" sensitivity, highest scan speed and long-lasting light source. Mon, 14 Aug 2017 07:38:00 +0000 Immunotherapy Safe for Diabetes 1? In a  placebo-controlled trial for treatments that could halt the progression of type 1 diabetes, scientists report that an immunotherapy was safe and showed metabolic effects. As many as 1.25 million Americans are living with type 1 diabetes, and the autoimmune disorder's prevalence has been increasing in recent decades, with roughly 40,000 people diagnosed each year. Thu, 10 Aug 2017 05:53:00 +0000 Do E-Cigarettes Help to Stop Smoking? The recent rise in e-cigarette use among US adult smokers is associated with a significant increase in smoking cessation, finds a study published in The BMJ. The study, based on the largest representative sample of e-cigarette users to date, provides a strong case that e-cigarettes have helped to increase smoking cessation at the population level. Wed, 26 Jul 2017 22:15:00 +0000 Free virtual issue of ChemMedChem The Royal Australian Chemical Institute is celebrating their 100th  anniversary.  Our colleagues from ChemMedChem are supporting the medicinal chemistry section of the RACI 100 conference in Melbourne, July 23-28 by sponsoring the poster prizes and launching the Virtual Issue on Medicinal Chemistry in Australia (, free to read until August 31st! Tue, 25 Jul 2017 10:03:00 +0000 Tracking Silver Nanoparticles With his forward-looking speech “There’s Plenty of Room at the Bottom” at the California Institute of Technology in the 50ies, the physicist and Nobel Prize winner Richard Feynman laid the foundation stone for the nanotechnology that developed many years later. Today, it is one of the fastest growing technologies in our time and has already entered our everyday life. Tue, 25 Jul 2017 08:36:00 +0000 Advanced Liquid Chromatography The measurement of samples by liquid chromatography is one of the last steps within the entire analysis cycle. Depending on the matrix, a more or less time consuming sample preparation is mandatory. This often involves clean-up and / or enrichment steps. Fri, 21 Jul 2017 06:43:00 +0000 TU Munich honors Phil S. Baran for pioneering research on synthesis of natural products The Department of Chemistry at the Technical University of Munich (TUM) and the Jürgen Manchot Foundation have granted the chemist Prof. Phil S. Baran the 2017 Wilhelm Manchot Research Professorship. With this distinction, the TUM honors his pioneering work on organic reactions creating new and efficient routes to natural products for the development of new medicaments. Thu, 13 Jul 2017 09:24:00 +0000 A Quantum Leap in Light Research Physicists have managed to capture the behavior of extremely short laser pulses during focusing by means of very high spatial and temporal resolution. The results are of fundamental relevance to understanding the interactions between light and matter and will make it possible to control electron movements and chemical reactions to an extent that was previously not feasible. These insights into fundamental physics will particularly profit further research into new radiation sources and in the field of light wave electronics. Thu, 13 Jul 2017 09:15:00 +0000 Feasible Measured Values Since the start of the photometry compendium, we have collected the most frequent requests about the subject "How do you achieve good measured results?" and compiled them into a list of favorites. Here, important subjects include the "Limit of the measurable" and "Recognize error sources". They are therefore summarized into these two topic blocks and clarified by means of the example of COD measurement. Tue, 11 Jul 2017 06:58:00 +0000 Mixer Mill MM 400 from Retsch: New adapters for rapid and efficient cell disruption and sample homogenization Retsch’s mixer mill MM 400 is a true multi-purpose mill in the lab. It is ideally suited for the disruption of biological cells as well as DNA/RNA and protein recovery. Also it is used for mixing and homogenizing powders and suspensions within seconds. Thu, 29 Jun 2017 12:03:00 +0000 2017 WITec Paper Award for Outstanding Scientific Publications The winners for the 2017 WITec Paper Award have been announced. From nearly 60 submissions, the jury selected the top three publications from Ireland, Portugal and Germany: they show in remarkable detail how information on the chemical and structural composition of a material, obtained through this non-destructive technique, can lead to a more comprehensive understanding of a wide range of materials. They used WITec correlative confocal Raman microscopes to study transition metal dichalcogenides, textile fibers and cement. Thu, 29 Jun 2017 08:37:00 +0000 Silicon-Based Tandem Solar Cells Today, wafer-based crystalline silicon solar cells dominate the photovoltaic (PV) market, with a market share of more than 90%. Further cost reductions for this technology can be achieved by developing silicon-based tandem solar cells employing low-cost, abundant, and non-toxic metal oxide materials. Such tandem cells can increase the conversion efficiency of silicon solar cells beyond their conventional limitations with obvious economic and environmental benefits.   Introduction Mon, 26 Jun 2017 12:55:00 +0000 Cancer Cells May Streamline Their Genomes in Order to Proliferate More Easily Research from the Stowers Institute provides evidence suggesting that cancer cells might streamline their genomes in order to proliferate more easily. The study, conducted in both human and mouse cells, shows that cancer genomes lose copies of repetitive sequences known as ribosomal DNA. While downsizing might enable these cells to replicate faster, it also seems to render them less able to withstand DNA damage. Fri, 23 Jun 2017 10:46:00 +0000 Do Proton Pump Inhibitors Increase Risk of Alzheimer's Disease? Proton pump inhibitors (PPIs) are medications used to treat digestive problems such as ulcers and reflux disease by reducing the body's production of the acid that helps us digest food. Ulcers are sores that develop on the lining of our digestive system; when they develop in the upper part of the small intestine they are called "duodenal ulcers." Reflux disease is a condition in which stomach acid or other fluids in the digestive system irritate our food pipe, also known as the esophagus. Fri, 23 Jun 2017 08:52:00 +0000 New Impact Factors Released If you are interested in seeing how the impact factors of the peer-reviewed journals from Wiley have changed, our colleagues from Chemistry Views have assembled the data and put it into a well-structured format. Please find all the details here. Fri, 23 Jun 2017 08:32:00 +0000 OptRF long-term testing of reagent-free measurement The wastewater treatment plant Peißenberg permitted WTW to perform long-term testing of the reagent-free measurement of COD and nitrate for a period of approx. 6 weeks. Two different WTW reagent-free measuring methods were tested: One was the IQ Sensor Net spectral sensor, the other was the new reagent-free photometry (OptRF) with the photoLab® 7600 UV-VIS. These two methods were compared to laboratory results from photometric cuvette tests. Thu, 22 Jun 2017 13:19:00 +0000 IDS goes wireless Wireless transmitter modules for full freedom of movement when measuring pH,conductivity, dissolved oxygen and turbidity with IDS sensors! Measure comfortably in confined spaces, e.g. under laboratory hoods and laminar flow benches. Thu, 22 Jun 2017 11:16:00 +0000 20 Years of Raman Imaging The Raman imaging company Witec celebrates its 20th Anniversary. It was founded in 1997 as a 3-person spin-off from the Physics Department of the University of Ulm and has grown into a company of 60 employees including the Ulm headquarters and its branch offices in Spain, China, Japan, Singapore and the USA. As reflected in the company’s maxim "Focus Innovations" Witec’s success is based on introducing new technologies and a commitment to maintaining customer satisfaction with high-quality, flexible and empowering products. Wed, 21 Jun 2017 10:24:00 +0000 REAfinity Recombinant Antibodies Miltenyi Biotec’s recombinantly engineered REAfinity Antibodies for flow cytometry are produced under standardized production processes starting from a defined DNA sequence, ensuring high purity and lot-to-lot consistency. These antibodies do not display any undesired mixtures of heavy and light immunoglobulin chains, which is often the case with conventional monoclonal antibodies. In addition, site-specific mutations eliminate non-specific binding of antibodies to Fcg receptors, thereby avoiding background signal. Tue, 20 Jun 2017 14:55:00 +0000 MACS GMP T Cell TransAct from Miltenyi Biotec MACS GMP T Cell TransAct is a ready-to-use reagent for efficient in vitro activation and expansion of human T cells. Also available in research grade. Tue, 20 Jun 2017 14:46:00 +0000 Waters Introduces LiveID Software for Real-Time, Direct-From-Sample Food Analysis and Plant Phenotyping Waters Corporation introduced its new LiveID Software for near- instantaneous, direct-from-sample measurement and classification of food products including meat and crops by Waters’ quadrupole, time-of-flight (QTof) mass spectrometers. Thu, 08 Jun 2017 12:57:00 +0000 Karl Deisseroth wins 4 million euros Fresenius Research Prize Karl Deisseroth, MD, PhD, a Stanford University professor of bioengineering and of psychiatry, has won the 2017 Fresenius Research Prize for his pioneering work in two distinct biomedical technologies — optogenetics and hydrogel-tissue chemistry — and for exploring his clinical specialty, depression, at the level of its underlying neural circuitry.  Deisseroth, who holds the D.H. Chen Professorship and is a Howard Hughes Medical Institute investigator, accepted the award today at a ceremony in Berlin. He will also give a talk, to be followed by a symposium, on June 1. Thu, 01 Jun 2017 12:35:00 +0000 Validation of X-Ray Fluorescence X-Ray Fluorescence is a powerful alternative to Inductively Coupled Plasma Optical Emission Spectrometry technique. A benchmarking of EDXRF instruments was launched to maintain awareness about their analytical performance capabilities and for allowing up-to-date recommendations to factory end-users. An EDXRF benchmarking methodology is explained with the description of the different steps, the critical points to respect in order to ensure a proper validation and the key performance criteria on which to focus. Introduction Wed, 31 May 2017 11:27:00 +0000 Detecting Weak Protein Interactions Protein-protein interactions have been implicated in cell growth, cell signaling, morphology, apoptosis, and a variety of additional cell processes. However, weak or transient protein interactions have proven difficult to study using traditional affinity purification. Exclusion-based Sample Preparation (ESP) can accelerate workflows and enable the study of weak interactions, which may reveal new targets for drug discovery. Wed, 31 May 2017 08:13:00 +0000