High-Field Asymmetric Waveform Ion Mobility Spectrometry

  • Fig. 1: Diagram of use of FAIMS for separationFig. 1: Diagram of use of FAIMS for separation

It is possible to increase the sensitivity for a target compound in the presence of high-level background impurities by removing the dosing vehicle using a High-Field Asymmetric waveform Ion Mobility Spectrometry (FAIMS) gas phase separation prior to mass spectrometry analysis. This article will discuss the FAIMS technique and present an example of how to reduce ion suppression in pharmaceutical studies.

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