Speeding up Mass Spectrometry

Determining the Effect of Mass Spectrometry Scan Speeds on Data Reproducibility for Metabolomics Analyses

Recently, there has been a trend towards faster chromatography for qualitative mass spectrometry applications, resulting in narrower chromatographic peak widths. As a result, slow-scanning mass spectrometers have been challenged with trying to acquire sufficient data to define these narrow peaks adequately. In this work, we sought to evaluate the mass spectrometer scan speed required to provide accurate, reproducible data when coupled to high speed LC systems in a metabolomics workflow.



AB Sciex
LV Nieuwerkkerk a/d IJsse
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The Netherlands
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