Foundation Funds 78
New Innovative Global Health Projects
The Bill & Melinda Gates Foundation announced 78 grants of US$100,000 each in the latest round of Grand Challenges Explorations. Grants include the development of a low-cost cell phone microscope to diagnose malaria, study of the strategic placement of insect-eating plants to reduce insect-borne diseases, and investigation of nanoparticles to release vaccines when they come in contact with human sweat. The grants support research across 18 countries and six continents. This year's European grantees are based at universities, research institutes and non-profit organizations. The winners represent groups in Germany, Sweden, Norway and the UK.
Some examples of the breadth of projects funded this round include:
More effective vaccines:
- Sweat-triggered vaccine delivery: Carlos Alberto Guzman of the Helmholtz Centre for Infection Research in Germany with Claus-Michael Lehr and Steffi Hansen of the Helmholtz-Institute for Pharmaceutical Research will develop nanoparticles that penetrate the skin through hair follicles and burst upon contact with human sweat to release vaccines.
- A "seek-and-destroy" laser vaccine: Owain Millington and Gail McConnell of University of Strathclyde in the United Kingdom will use existing imaging systems to identify and destroy Leishmania parasites with a targeted laser;
- Treating worm infections to improve vaccine effectiveness: Susanne Nylén Spoormaker of the Karolinska Institute in Sweden will research whether treating patients for worm infections prior to vaccinations can improve the ability of the immune system to respond effectively to vaccines.
New strategies to fight malaria:
- Cell phone microscope to diagnose malaria: Aydogan Ozcan of the University of California, Los Angeles in the U.S. will test a low-cost, compact cell phone microscope to diagnose malaria in field settings.
Solutions to promote family health:
- Vitamin A probiotics to combat diarrhea: Douglas Watson and colleagues of SRI International in the U.S. will develop probiotic bacteria that produce Vitamin A to stimulate a healthy gastrointestinal tract in children and reduce diarrheal diseases, the second-leading cause of childhood death.