Jun. 30, 2010
NewsCompany News

Advancing Emerging Glycomics Research

Agilent Technologies, National Institute for Bioprocessing Research and Training

  • Professor Pauline Rudd in the Dublin-Oxford Glycobiology Lab, will use Agilent LC-MS/MS technology to research glycomics (Source: Agilent Technologies)Professor Pauline Rudd in the Dublin-Oxford Glycobiology Lab, will use Agilent LC-MS/MS technology to research glycomics (Source: Agilent Technologies)

Agilent Technologies and the Agilent Foundation announced that Professor Pauline Rudd has received an Agilent Thought Leader Award in support of her emerging glycomics research. The award includes a grant of funding and instruments to the National Institute for Bioprocessing Research and Training (NIBRT) in Dublin, Ireland. The goals of the research are to develop novel approaches to analyze protein glycosylation which will assist in the characterization of recombinant protein drugs, and to study potential glycan biomarkers associated with disease using liquid chromatography/mass spectrometry.
As leading experts in glycomics research, Professor Rudd's group members have developed a new technology for high-throughput, detailed, quantitative glycan analysis at NIBRT's Glycobiology Group Laboratory. The NIBRT Glycobiology Lab is at the forefront of fully automating technologies for glycan release and labelling, HPLC analysis, and exoglycosidase sequencing. Dedicated software and experimental databases enable computer assisted data analysis. The platform is allied to MS technologies to obtain further structural characterization and to provide a service that supports the drug development pipeline of leading pharmaceutical companies.
Rudi Grimm, Ph.D., director of science and technology for Agilent's Life Science Group, will work closely with Professor Rudd to provide technical expertise and serving as the primary contact with Agilent. Dr. Grimm created the opportunity for the grant by working with Agilent's University Relations Program and Life Sciences Group to secure funding and instrumentation. This is the first award from Agilent's new Thought Leader Program, which promotes fundamental advances in the life sciences by contributing financial support, products and/or expertise to the research of influential thought leaders.

http://www.agilent.com

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