Apr. 16, 2015

Bookreview: "Applied NMR Spectroscopy for Chemists and Life Scientists"

  • Applied NMR Spectroscopy for Chemists and Life Scientists, Author: Oliver Zerbe and Simon JurtApplied NMR Spectroscopy for Chemists and Life Scientists, Author: Oliver Zerbe and Simon Jurt

"Applied NMR Spectroscopy for Chemists and Life Scienctists" is the title of the book by Prof. Dr. Oliver Zerbe and Simon Jurt.

Although it might be the most important analytical method for structure determination in chemistry, NMR spectroscopy was often introduced in the university curriculum from a theoretical point of view. Due to the ongoing rapid development of the technique, enabling applications beyond small molecules (all classes of biomolecules and monitoring of molecular interactions as prominent examples), also the requirements for timely introduction of NMR spectroscopy changed fundamentally. Nowadays, direct transfer of theoretical models to experimental practice is mandatory. Oliver Zerbe and Simon Jurt follow in their textbook consequently this unique approach: The necessary quantum mechanical background is introduced at an appropirate level to understand all relevant new concepts such as multidimensional methods.

Why did you choose an application-oriented approach to writing this book?

The purpose was to provide all scientists who actually record spectra themselves, who want to understand basic NMR theory up to a fairly advanced level, or who need help in the interpretation of spectra, with the necessary knowledge.

How viable are benchtop NMR spectrometers for standard analytics?

We have no experience with benchtop systems here in Zurich. However, we feel for our purpose here in chemistry - both in teaching as well as in research - we need full spectrometers capable for performing all standard experiments (1D and 2D experiments). We actually use 300 and 400 MHz spectrometer for student training in the advanced practical chemistry courses.

What was the reason to write this book?

We felt there is a need for a book that covers both practical as well as theoretical aspects of NMR and takes care of the fact that students measure spectra themselves (in contrast to the situation 20 years ago where samples were handed into a service).

We also wanted to report on assignment techniques and strategies, an often-neglected aspect. The book should be suitable for beginners but be sufficient for all chemists, and other scientists interested in this technique (expect for those who do a PhD in the field of NMR).

Which background information does the reader need?

The reader needs no special background; all topics are developed from scratch. However, we admit that some basic understanding of principles in physical chemistry would be helpful. Some readers with very limited background may not understand every chapter, but we strongly feel that everyone interested in NMR will benefit.

Prof. Dr. Oliver Zerbe
is the head of the NMR department and group leader at the University of Zurich scince 2003. He studied chemistry and obtained his PhD in the group of Wolfgang von Philipsborn in Zurich. Upon a postdoctoral stay in the group of Kurt Wüthrich, he conducted his habilitation in Medicinal Chemistry with Gerd Folkers. His main interests are structures of proteins, particularly of membrane proteins.

Simon Jurt
has been working for more than ten years in the NMR department of the University of Zurich after studies in chemistry at the University of Applied Sciences in Bern. He is responsible for maintenance of NMR spectrometers and practical NMR courses.

1. Edition December 2013
548 pages, Softcover
ISBN 978-3-527-32774-4
Wiley-VCH, Weinheim

Sample Chapter (pdf): http://www.wiley-vch.de/

Take a look at an article by Oliver Zerbe and Simon Jurt:
NMR in Chemistry and the Life Sciences
New Challenges and Opportunities



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