Lab-on-chip Technique: Detection of Pathogenic DNA
Laboratory techniques, usually complex ones, are required to detect pathogens. Sometimes we need a quick result, or there is no laboratory nearby. Portable and fast methods of detection that are also sensitive, reliable, quantitative, and effective over a broad range of concentrations are thus highly desirable. In the journal Angewandte Chemie, American researchers have now introduced a new approach for a lab-on-chip technique for the detection of pathogens by means of their genetic material. The method is so sensitive that it was able to detect as few as 16 copies of DNA from salmonella-in less than an hour.
Read more within the original publication:
Kuangwen Hsieh, Adriana S. Patterson, Dr. B. Scott Ferguson, Prof. Kevin W. Plaxco, Prof. H. Tom Soh: Rapid, Sensitive, and Quantitative Detection of Pathogenic DNA at the Point of Care through Microfluidic Electrochemical Quantitative Loop-Mediated Isothermal Amplification. Angew. Chem. Int. Ed. doi: 10.1002/anie.201109115