Laboratory Journal – Business Web for Users in Science and Industry en Data Analysis Tool Empowers the People Data production doubles each year, but data scientists, who wrangle insights from reams of data, are in short supply. To bridge this gap, a team at A*STAR has developed a fully automatic, web-based system that puts the power of big data analysis in the hands of laypeople. Fri, 20 Apr 2018 10:52:00 +0000 Activity in the Brain James Poulet's lab at the MDC uses advanced techniques to monitor the activity of networks of single sensory neurons in the brain. By listening in on hundreds of conversations, the scientists have discovered how a single signal from one cell manages to attract attention. Thu, 19 Apr 2018 07:45:00 +0000 Nanoparticles in Food Packaging “We found that zinc oxide (ZnO) nanoparticles at doses that are relevant to what you might normally eat in a meal or a day can change the way that your intestine absorbs nutrients or your intestinal cell gene and protein expression,” said Gretchen Mahler, associate professor of bioengineering. ZnO nanoparticles in certain canned goods Fri, 13 Apr 2018 12:38:00 +0000 First Room Temperature Maser Using Diamond Developed The world’s first continuous room-temperature solid-state maser has been developed by UCL and Imperial College London scientists. The breakthrough, made using a diamond held in a ring of sapphire, opens up the possibility for masers (microwave amplification by stimulated emission of radiation) being used in a wide variety of applications such as medical imaging and airport security scanning. Thu, 05 Apr 2018 07:35:00 +0000 Duckweed for Human Nutrition Human nutrition has always been an area of high priority, especially in the present era where people are becoming more and more aware of health benefits and / or side effects of their daily food. Of course, this is aided by the progressive and advanced research in the area of human nutrition. We are now going to talk about a plant (rather a plant family), which is a good component of human diet. These plants are commonly called duckweeds with the Latin name Lemnaceae. They are free-floating aquatic monocots. Wed, 04 Apr 2018 09:00:00 +0000 Artificial Molecules That Mimic DNA Not only can synthetic molecules imitate the structures of their biological counterparts, they can also assume their functions and even outcompete them. This has recently been demonstrated by researchers from the CNRS, Inserm and Bordeaux University, who have developed an artificial sequence mimicking the surface features of DNA for the first time. This artificial molecule is able to inhibit the activity of several DNA-binding enzymes, including the one used by HIV to insert its genome into that of its host cell. Wed, 04 Apr 2018 08:18:00 +0000 From a Gummi Bear to a Skin Model It is the first interface of contact between our bodies and the environment. It is our protective armor, keeping us safe, healthy and comfortable every single day. It is our skin. Wed, 04 Apr 2018 08:00:00 +0000 GC is Fine For Compounds in Wine Although wine has been produced in Turkey for thousands of years, it is only relatively recently that there have been concerted attempts to apply scientific methods in order to produce high-quality products. Wine is typically produced by a pressing process, but it possible to obtain some liquid from the macerated material without pressing (free-run juice); wines from this free-run juice typically differ from those made from a pressing process. Tue, 03 Apr 2018 12:33:00 +0000 Unequivocal HER2 Detection and Quantification Overexpression of the HER2 gene is predictive of patient response to targeted therapies, but standard HER2 detection methods, immunohistochemistry and fluorescence in situ hybridization, are both technically demanding and often produce equivocal results. Droplet Digital PCR quantification technology, however, may enable a reliable and robust reflex test for HER2 in ambiguous tumor samples. Tue, 03 Apr 2018 08:15:00 +0000 Nanocompartments Combining natural biomolecules with synthetic polymer vesicles enables creation of bio-inspired, nanometer-sized catalytic compartments. Inside the nanocompartments, glucose meta-bolites can be converted by an enzyme and released through engineered pore proteins embedded in the polymer vesicle membrane. Tue, 03 Apr 2018 07:20:00 +0000 The Detector In recent years, mass spectrometric detectors have increasingly found their way into analytical laboratories. Although the UV detector is still “the” standard HPLC detector, it is likely to be replaced by simple mass spectrometers (MS) in the near future. Why the coupling between micro-LC and MS is a true “marriage in heaven”, we would like to explain below. Tue, 03 Apr 2018 06:00:00 +0000 The Body’s Library Why don’t identical twins look the same? Why do famines either lead to a higher risk for diseases or an extended lifespan? Why do some kinds of stress make us ill, and others do not? All of these questions can be reduced to one common denominator: The variable readability of our DNA – the so-called epigenome. Just like a library, it regulates who has access at which time to which information. The epigenome enables the development of complex life forms, but is also the source of many diseases. Tue, 03 Apr 2018 06:00:00 +0000 Recycling of Lithium Ion Batteries Lithium ion batteries (LIBs) are used in modern day portable consumer electronics like laptops, smartphones or tablets due to their high energy density and high specific energy. Furthermore, as the most interesting battery technology for pure and hybrid electric vehicles, there exists a widespread application of LIBs in private and industrial processes. Fri, 30 Mar 2018 11:30:00 +0000 Petahertz electronics in diamond The rapid progress in picosecond and femtosecond ultrafast lasers that happened in the 80’s has allowed bridging the gap between electronics and optics. The new connection between these two fields has since given rise to a wealth of new technologies and scientific insights. Fruits from these pioneering years include the fields of terahertz science and technology and high-speed optoelectronics. Fri, 30 Mar 2018 07:45:00 +0000 Chemical Synthesis With Artificial Intelligence The board game Go was long considered to be a bastion reserved for human players due to its complexity. Nowadays, however, the world’s best players no longer have any chance of winning against the “AlphaGo” software. Researchers at the University of Münster have now demonstrated that the recipe for the success of this software can be put to excellent use to plan chemical syntheses. Thu, 29 Mar 2018 06:36:00 +0000 Intracellular Drug Delivery Researchers at Oregon State University and Oregon Health & Science University have created new nanomaterials able to cross cell membranes, establishing a novel platform for the intracellular delivery of molecular drugs and other cargo. The researchers explored how to tune the size, shape and morphology of materials known as cell-penetrating self-assembling peptide nanomaterials, or CSPNs. Wed, 28 Mar 2018 07:51:00 +0000 Atomistic Insights into Electrocatalysis Electrocatalysts are important for many industrial processes as they enhance the conversion of electrical energy into chemical energy and thus help to store excessive electrical energy generated by renewable energy resources. Tue, 27 Mar 2018 06:57:00 +0000 Second Research Xchange Forum at Sartorius How to win a Nobel Prize: Dr. Stefan W. Hell gave an inspirational speech on this subject today at the opening of the second Research Xchange Forums hosted by Sartorius. A professor and scientist at the Max Planck Institute for Biophysical Chemistry in Germany, he addressed an audience of more than 140 guests at Sartorius College in Göttingen, describing the path he took that led him to winning a Nobel Prize in 2014 – and what the secrets of such success are. Mon, 26 Mar 2018 10:27:00 +0000 Generation of a Stable Biradical Boron has a range of uses throughout everyday life, from laundry bleaches to heat-proof glass and ceramics. Chemists at Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany, have a particular interest in the chemistry this element, and have been researching the fundamental properties of boron for years. These researchers have now succeeded in twisting molecules with multiple bonds between boron atoms, leading to unusually stable biradicals. Thu, 22 Mar 2018 15:01:00 +0000 Room Temperature Maser to Amplify Weak Signals The spacecraft Voyager 2 has travelled a barely imaginable 17 billion kilometers from Earth and continues to send signals to the ground station. This is made possible by the maser technology, which works on similar principles to the laser and is able to amplify weak microwave signals almost noise-free. For regular communication on Earth, this technology is rarely used because it works only at low temperatures. However, a research team at the London Center for Nanotechnology and the University of Saarland has now developed a maser that can be used at room temperature. Thu, 22 Mar 2018 10:09:00 +0000 Choose Olympus’ Award-winning CX3 Series for Routine Microscopy Olympus’ CX3 series of upright microscopes for routine microscopy delivers superior ergonomics and reduces fatigue during long periods of use. The CX23 microscope, recognized with an “iF Design Award” in 2017, combines reliable optical quality with bright, uniform illumination – perfect for educational settings. Wed, 21 Mar 2018 15:11:00 +0000 Low-tech Solutions to Improve Water Quality Most of us are used to turning on a tap and water coming out. We rarely question whether this will happen or whether the water is clean enough to bathe in or drink. Though the process of maintaining water quality is practically invisible to most of us, removing bacteria and contaminants from water requires a lot of effort from both humans and treatment systems alike. Tue, 20 Mar 2018 15:42:00 +0000 Commonly Used Drugs Affect Our Gut Bacteria One in four drugs with human targets inhibit the growth of bacteria in the human gut. These drugs cause antibiotic-like side-effects and may promote antibiotic resistance, EMBL researchers report in "Nature". The research team screened over 1000 marketed drugs against 40 representative bacteria from the human gut, and found that more than a quarter of the non-antibiotics (250 out of 923) affect the growth of at least one species in the microbiome. EMBL group leaders Peer Bork, Kiran Patil, Nassos Typas, and Georg Zeller led the work. Tue, 20 Mar 2018 11:43:00 +0000 Superior Working Comfor with the Acura Manual Pipettes from Socorex Ergonomics is a key word for the Acura manual pipette line. From soft shape to smoothest activation, every detail drives to superior comfort level and stress-free pipetting. Tue, 13 Mar 2018 15:50:00 +0000 Spectroscopic Thermometer for Nanomaterials A scientific team led by the Department of Energy’s Oak Ridge National Laboratory has found a new way to take the local temperature of a material from an area about a billionth of a meter wide, or approximately 100,000 times thinner than a human hair. Tue, 13 Mar 2018 14:04:00 +0000