Laboratory Journal – Business Web for Users in Science and Industry en Webinar: Possibilities of Raman and NIR spectroscopy Do you want to discover the possibilities of Raman and NIR spectroscopy in incoming materials inspection to reduce workload pressures and achieve significant cost savings? Fri, 20 Sep 2019 08:50:00 +0000 Welcome Indoors, Solar Cells Swedish and Chinese scientists have developed organic solar cells optimised to convert ambient indoor light to electricity. The power they produce is low, but is probably enough to feed the millions of products that the internet of things will bring online. Mon, 16 Sep 2019 14:04:00 +0000 The Genetics of Cancer University of Delaware molecular biologist Mona Batish and collaborators at Harvard Medical School and University of California, Los Angeles, have identified a new circular ribonucleic acid (RNA) that increases tumor activity in soft tissue and connective tissue tumors. Finding this new Fri, 13 Sep 2019 07:39:00 +0000 Artificial Intelligence Speeds Up Photodynamics Simulations The prediction of molecular reactions triggered by light is to date extremely time-consuming and therefore costly. A team led by Philipp Marquetand from the Faculty of Chemistry at the University of Vienna has now presented a method using artificial neural networks that drastically accelerates the simulation of light-induced processes. Thu, 12 Sep 2019 06:00:00 +0000 All of YouTube in a Single Teaspoon Researchers at the Technion–Israel Institute of Technology in Haifa and the Interdisciplinary Center (IDC) Herzliya have demonstrated a significant improvement in the efficiency of the process needed to store digital information in DNA. In a paper published in Nature Biotechnology ("Data storage in DNA with fewer synthesis cycles using composite DNA letters"), the group demonstrated storage of information in a densit Tue, 10 Sep 2019 05:29:00 +0000 Nanowires Replace Newton's Famous Glass Prism Scientists have designed an ultra-miniaturised device that could image single cells without the need for a microscope or make chemical fingerprint analysis possible from within a smartphone camera. The device, made from a single nanowire 1000 times thinner than a human hair, is the smallest spectrometer ever designed. It could be used in potential applications such as assessing the freshness of foods, the quality of drugs, or even identifying counterfeit objects, all from a smartphone camera. Tue, 10 Sep 2019 05:12:00 +0000 Determination of Intra- and Extra-cellular Vitamin C Dynamics The redox-sensitive inter-conversion of ascorbic acid (ASC) and its oxidized form dehydroascorbic acid (DHA) in intracellular and extracellular environments is of exceptional interest at the forefront of metabolomics and pharmaceutical research, including high-dose vitamin C cancer therapy. A chromatographic protocol to instantly determine these vitamers in both forms from cellular extracts, without any labeling or pretreatment has been reported earlier. [1] Background Sat, 07 Sep 2019 05:32:00 +0000 A Molecular 'Atlas' of Animal Development In a paper in Science this week, Penn researchers report the first detailed molecular characterization of how every cell changes during animal embryonic development. The work, led by the laboratories of Perelman School of Medicine's John I. Fri, 06 Sep 2019 04:35:00 +0000 Closing In on Elusive Particles In the quest to prove that matter can be produced without antimatter, the GERDA experiment at the Gran Sasso Underground Laboratory in Italy is looking for signs of neutrinoless double beta decay. The experiment has the greatest sensitivity worldwide for detecting the decay in question. To further improve the chances of success, a follow-up project, LEGEND, uses an even more refined decay experiment. Thu, 05 Sep 2019 18:20:00 +0000 Back to the Roots in Disinfection In times of growing water scarcity and the formation of bacterial resistance against standard antibiotics [1], classical chemical disinfectants, such as chlorine dioxide, elemental chlorine and hypochlorite, experience a renaissance in water treatment. A problem of these disinfectants is the formation of so-called disinfection by-products (DBPs), such as chlorate (ClO3-) or perchlorate (ClO4-), which are undesirable and need to be monitored. Thu, 05 Sep 2019 10:57:00 +0000 Ion Chromatography in Water Analysis Since the 1980’s, Ion Chromatography was developed into a powerful and sensitive tool for Ion Analysis. Nowadays, anion- and cation-chromatography is a well-established technique and used for the determination of a large number of ions in different matrices. As the presentation of an overview of the wide field of Ion Chromatography (IC) is clearly beyond the scope of this short paper, the book of Joachim Weiss [1] is strongly recommended. This paper focuses on the analysis of anions in water and waste water and aims to motivate to use this technique. Wed, 04 Sep 2019 10:13:00 +0000 Opening the Hatch to Heal the Break LMU researchers have determined the structure of a key enzyme complex that is involved in DNA repair, and traced the cycle of conformational changes that it undergoes while performing its biochemical function. Tue, 03 Sep 2019 15:01:00 +0000 SiLA 2 - The Emerging Standard for Lab Automation Silvana K. enters her lab, looks at the display of her smartphone and finds all lab devices listed. She selects the balance, let it tare and weighs her sample. The values of tare and weight are automatically transferred into her electronic lab notebook (including further (meta-)information, like time and date, lab, room temperature and air pressure). Tue, 03 Sep 2019 08:00:00 +0000 Why Are We Different Sizes? The body size of a living creature has a direct impact on its fitness - from the simplest animal and plant organisms right up to human beings. The individual size or height is therefore an important criterion for the ability of an organism to succeed in the competition for resources or reproduction. We basically assume that there is similar genetic information within a species, which in theory should lead to relatively uniform body sizes. Tue, 03 Sep 2019 05:02:00 +0000 Detecting Rotating Light A combination of two materials that can detect rotating light has been demonstrated by physicists at RIKEN (Physical Review Letters, "Photoinduced Rashba spin-to-charge conversion via an interfacial unoccupied state"). This approach could help develop information processing devices that have ultralow power consumption. Fri, 30 Aug 2019 07:47:00 +0000 From Crystals to Glasses Theoretical physicists from SISSA and the University of California at Davis lay brand new foundations to such a fundamental process as heat transport in materials, which finally allow crystals, polycrystalline solids, alloys, and glasses to be treated on the same solid footing. Mon, 26 Aug 2019 10:09:00 +0000 How Pressure-sensing Piezo Proteins Work A team of scientists from Weill Cornell Medicine and The Rockefeller University has illuminated the basic mechanism of Piezo proteins, which function as sensors in the body for mechanical stimuli such as touch, bladder fullness, and blood pressure. The discovery is a feat of basic science that also opens up many new paths of investigation into the roles of Piezo proteins in human diseases and potential new therapeutic strategies. Thu, 22 Aug 2019 05:01:00 +0000 New Protein Spin Labelling Technique University of Konstanz researchers develop a new site-directed spin labelling approach based on genetically encoded noncanonical amino acids amenable to Diels-Alder chemistry as well as a new spin label, PaNDA. Tue, 20 Aug 2019 16:48:00 +0000 The Journey of the Pollen For allergy sufferers, the pollination period is a tough time, whereas for plants it is the opportunity to reproduce: in addition to the wind, insects, in particular, carry the pollen from one flower to another to pollinate them. During this transport, the pollen must repeatedly attach to and detach from different surfaces. To date, the underlying adhesive mechanisms have hardly been studied so far. Tue, 20 Aug 2019 16:36:00 +0000 How Synthetic Cells are Fighting Infectious Bacteria A team of researchers at the DWI - Leibniz Institute for Interactive Materials in Aachen is pioneering a revolutionary concept for antimicrobials. Mon, 19 Aug 2019 16:12:00 +0000 Nanoparticle Therapy Targets Lymph Node Metastases Metastasis, in which cancer cells break free from the primary tumor and form tumors at other sites, worsens the prognosis for many cancer patients. The lymph nodes - glands of the immune system located throughout the body - are typically the traveling cells' first destination. Now, researchers have developed a strategy to target metastases in lymph nodes for destruction, before they can cause cancer at other locations. They report their results in ACS Nano. Thu, 15 Aug 2019 05:15:00 +0000 Rewriting the Periodic Table at High Pressure The periodic table has been a vital foundational tool for material research since it was first created 150 years ago. Now, Martin Rahm from Chalmers University of Technology presents a new article which adds an entirely new dimension to the table, offering a new set of principles for material research. Thu, 15 Aug 2019 04:57:00 +0000 Chemical Analysis of Cannabinoids In the past years the legal acceptance of medicinal cannabis and the gradual international acceptance of recreational cannabis, and last but not least, because of the belief in CBD-oil as a wonder drug, there is a high demand for proper methods of analysis for cannabis preparations. Tue, 13 Aug 2019 05:34:00 +0000 CBD-Rich Cannabis – the Legal Marijuana The availability and the consumption of cannabis products rich in cannabidiol (CBD), legally accessible in Switzerland if the total Δ9-tetrahydrocannabinol (THC) content is lower than 1%, is a widely debated issue in the media and poses a challenge for the judicial authorities. Tue, 13 Aug 2019 05:31:00 +0000 A Close Examination of Medical Cannabis Medical cannabis is already being used successfully for treatment of many diseases. Quality control is therefore of great importance. Among other things, total cannabinoid content and the ratio of the individual cannabinoids has to be determined, as different medical applications depend on the content of the individual cannabinoids. The optimization of regulated methods is difficult as changes, including co-injection with water, are not permitted. Tue, 13 Aug 2019 05:10:00 +0000