Laboratory Journal – Business Web for Users in Science and Industry en Turning Up the Heat on Protein Interactions Protein-protein interactions are at the heart of all cellular functions and biological processes. These interactions are carefully regulated in space and time to meet the cell’s requirements and are often disrupted in disease states. Wed, 20 Jun 2018 07:46:00 +0000 Apply for the Anton Paar Research Award Anton Paar invites researchers and scientists to submit projects for the first research prize for instrumental analysis and characterization with a value of 20,000 Euro. Tue, 19 Jun 2018 10:52:00 +0000 Devastating Plant Virus Is Revealed in Atomic Detail The complex 3D structure of one of the world’s most lethal families of plant viruses has been revealed in unprecedented detail by scientists at the University of Leeds. Geminiviruses are responsible for diseases affecting crops such as cassava and maize in Africa, cotton in the Indian subcontinent and tomatoes across Europe. Being able to see its structrure in great detail is vital as it could help virologists and molecular biologists better understand the virus lifecyle, and develop new ways to stop the spread of these viruses and the diseases they cause. Mon, 18 Jun 2018 09:05:00 +0000 Measuring Energy in Microscopic Machines What drives cells to live and engines to move? It all comes down to a quantity that scientists call “free energy,” essentially the energy that can be extracted from any system to perform useful work. Without this available energy, a living organism would eventually die and a machine would lie idle. Tue, 12 Jun 2018 07:55:00 +0000 Eppendorf at Achema 2018 - All about Bioprocessing The Eppendorf booth at the Achema is all about bioprocessing. The Eppendorf laboratory team will show a typical bioprocess workflow and present innovative solutions to optimize the lab processes. Get to know Eppendorfs new bench-scale BioFlo 120 bioprocess control station, and our comprehensive portfolio of autoclavable, single-use, and sterilize-in-place bioreactors for process development at small scale to pilot scale production. Sun, 10 Jun 2018 12:22:00 +0000 Cell-Like Nanorobots Clear Bacteria and Toxins from Blood Engineers at the University of California San Diego have developed tiny ultrasound-powered robots that can swim through blood, removing harmful bacteria along with the toxins they produce. These proof-of-concept nanorobots could one day offer a safe and efficient way to detoxify and decontaminate biological fluids. Researchers built the nanorobots by coating gold nanowires with a hybrid of platelet and red blood cell membranes. Fri, 08 Jun 2018 02:16:00 +0000 Endress+Hauser receives the German Innovation Award This year was the first time that the German Innovation Award recognized products that set themselves apart from currently available solutions through their added value. “With the innovative Promass Q flowmeter, Endress+Hauser has set a new standard for the precision measurement of quantity, density and temperature of a flowing fluid. After all, precise measurements increase product quality, reduce the reject rate and cut costs,” said Andrej Kupetz, Head of the German Design Council and Chairman of the German Innovation Award jury. Thu, 07 Jun 2018 08:48:00 +0000 Easy Cell Transdifferentiation Fresh or frozen human blood samples can be directly transformed into patient-specific neurons to study disorders such as schizophrenia and autism, Stanford researchers find. Human immune cells in blood can be converted directly into functional neurons in the laboratory in about three weeks with the addition of just four proteins, researchers at the Stanford University School of Medicine have found. Thu, 07 Jun 2018 05:20:00 +0000 Nobel Laureate Sir Fraser Stoddart at the Wiley Booth The Nobel Prize Laureate Sir Fraser Stoddart will be signing copies of his book "The Nature of the Mechanical Bond" at our booth (hall 5.1 / 6.1 B8) at the Achema on Monday, the 11th of June 2018 from 3-4 p.m. Tue, 05 Jun 2018 11:26:00 +0000 Precision Ceramic and Glass Microcomponents Currently celebrating 70 years of facilitating scientific innovation, Goodfellow is a leading global supplier of metals, alloys, ceramics, glasses, polymers, compounds, composites & other materials to meet the research, development & specialist production requirements of science & industry. The company has an extensive range of 70,000 catalogue products in multiple forms available off the shelf, most subject to free delivery within 48 hours and with no minimum order quantities. Sun, 03 Jun 2018 08:29:00 +0000 Chiral Nanostructures For the first time scientists have created a way to model the interaction between light and twisted molecules, as these molecules transition from left- to right-handed versions, or vice versa. The transitional forms offer a deeper insight into material symmetries and their unexpected behaviour could lead to improved design of telecoms components. Fri, 01 Jun 2018 10:11:00 +0000 Chip-Based Nanoscopy in HD Quality A waveguide chip that enables optical super-resolution microscopy (“nanoscopy”) on conventional microscopes with a resolution better than 50 nm has been developed by physicists in Germany and Norway [1]. The new technique is easy to use and does not rely on complex and expensive microscopes. Furthermore, the mass-producible waveguide chip offers a much larger field-of-view as compared to current techniques. This has the great potential to open up optical super-resolution microscopy to many more people with even new applications. Thu, 31 May 2018 12:52:00 +0000 Fighting the Doppler Broadening The central idea of spectroscopy is to shine a light with variable wavelength on matter and to observe the output spectra. If the light is in resonance with a transition from one quantum state to another, strong absorption will occur. By analyzing the position of absorption peaks, one can determine the structure of an atom or molecule and how it moves. A Key Issue of Spectroscopy Thu, 31 May 2018 08:30:00 +0000 Improving Superconducting Qubits The idea of a quantum computer can be traced back to Feynman’s talk at the 1981 conference on “The physics of quantum computation”: he recognized that simulation of nature should be quantum mechanical, “a wonderful problem, because it doesn’t look so easy” [1].  Indeed, building a quantum computer is not easy: it requires the so-called DiVincenzo criteria to be met [2]. In particular, the lifetime of a quantum bit (qubit) should be long enough, so that errors can be corrected and a useful computation performed. Thu, 31 May 2018 07:15:00 +0000 Stable Isotope Fingerprinting of Amino Acids In a world where food production is becoming more globalized and industrialized, consumers are increasingly concerned about food safety, traceability, and sustainability. This is particularly true for fish and seafood products because more than half of the world’s products now come from aquaculture. To reduce costs and impact on wild fish stocks, carnivorous fish such as salmon and trout are increasingly fed alternatives to fishmeal such as plant- and insect-based diets. Wed, 30 May 2018 09:00:00 +0000 Virtual Conference: Analytical Techniques for Advanced Materials For a 2nd year material science researchers from around the globe gathered for an innovative online experience where we explored the latest cutting edge analytical solutions used to enable the development of new and advanced materials. Wed, 30 May 2018 08:02:00 +0000 Non-Contact Measuring of Tiniest Currents Intensities of beam currents in particle accelerators or storage rings need to be measureable. Numerous measurement devices to determine the number of agitated electrically charged particles exist for this purpose. A large problem arises if the following is required: Wed, 30 May 2018 06:50:00 +0000 Read & Win: Direct Analysis in Real Time Mass Spectrometry Direct Analysis in Real Time (DART) is an atmospheric pressure ionization method. Invented in 2005, it has been evolving very fast in recent years. It is operated under ambient conditions and can be used to ionize gases, liquids, and solids. The resulting ions are analyzed in a mass spectrometer: Mass determination enables structure elucidation. Unlike most other ionization methods, DART does not require laborious sample preparation, as ionization takes place directly on the sample surface. Tue, 29 May 2018 12:23:00 +0000 I Think I Have Seen the Future … During this year’s analytica fair in Munich, I had the opportunity to see how the developers at Gilson plan to add connectivity to the bench in the lab. There are quite a few companies developing solutions, but this was the most complete concept I have seen so far. Tue, 29 May 2018 12:05:00 +0000 Miniaturized HPLC Systems In the academic environment, micro-LC played a major role in the early commercialization of HPLC systems in the 1960s. Although the technical requirements were significantly worse than today, many university research groups have succeeded in successfully demonstrating the much-cited advantages of miniaturized HPLC systems in the form of proof-of-concept studies. Tue, 29 May 2018 10:10:00 +0000 Is Variable Production “Science Fiction”? In “Star Trek - Next Generation”, nearly all items for everyday consumption such as food and beverages are produced by a single device, the replicator. For us today, this is science fiction. However, many devices of everyday life today are already more advanced than those that were still science fiction in the first Star Trek series. When we remember Captain Kirk’s “communicator” and compare it to our smartphones we can only smile. Tue, 29 May 2018 08:10:00 +0000 DIY Low-Budget Smartphone Photometer A LED photo sensor, designed as a kit and assembled more than 100 times by school groups, has been fundamentally revised. In the new version, the light detector is now a component of digital electronics and is connected to a Wifi- (WLAN-) enabled microprocessor, which transmits its data to a smartphone. At approx. 30 €, the price of the required components is quite moderate, and instead of the previously required multimeter, now any commercially available smartphone can be used. Tue, 29 May 2018 08:10:00 +0000 Polymer Analysis and Microplastics in the Environment The abbreviation TED-GC-MS describes a two-step method for volatile diagnostics originating from polymers at high temperatures. First the entire sample is pyrolized and the polymer specific decomposition products are trapped on a solid-phase adsorbent (Thermal Extraction). In a subsequent step the decomposition products are thermally desorbed, chromatographically separated and then identified with mass spectrometry. Tue, 29 May 2018 06:25:00 +0000 Photoswitchable Catalysis Depending on the lighting, the surface of appropriately crafted nanoparticles can change its topography. Researchers from the Institute of Physical Chemistry of the Polish Academy of Sciences have shown that the molecular mechanism they have designed makes it possible, by the use of light, to effectively uncover or hide catalyst molecules. The technique they present leads to qualitatively new possibilities to control the course of chemical reactions. Fri, 25 May 2018 09:23:00 +0000 Socorex Electronic Micropipette The Acura electro is making electronic pipetting more versatile, simpler and safer than ever. Extended range includes seven micro models (0.1 to 1000 µL), three macropipettes (0.1 - 10 mL) and eight multichannel instruments (0.1 to 350 µL). Thu, 24 May 2018 07:21:00 +0000