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Dec. 09, 2019
ScienceMedicine & Diagnostics
The Potential of Volatile Organic Compounds
The analysis of VOCs emanating from biological samples appears as one of the most promising approaches in metabolomics for the study of diseases. The presence of volatile markers has been explored in exhaled breath, urine, blood, saliva, ...
Oct. 09, 2019
ScienceMedicine & Diagnostics
Applications for ddPCR in Oncology
Treatment options for patients with cancer have been increasing in recent years, but not all patients respond to these treatments with the same success. Although precision medicines are now available to more patient populations than ever ...
Aug. 12, 2019
ScienceMedicine & Diagnostics
Measuring Biomarkers in Blood
The measurement of trimethylamine-N-oxide (TMAO) and branched-chain amino acids (BCAA) in blood is of interest as they are potential indicators of cardiovascular disease risk and diabetes respectively [1-5]. To date, the determination of ...
Apr. 03, 2018
ScienceMedicine & Diagnostics
Unequivocal HER2 Detection and Quantification
Overexpression of the HER2 gene is predictive of patient response to targeted therapies, but standard HER2 detection methods, immunohistochemistry and fluorescence in situ hybridization, are both technically demanding and often produce ...
Apr. 03, 2017
ScienceMedicine & Diagnostics
Detection of Bacteria and Antibiotic Resistance
Recent advances in micro and nanofabrication of sensors are enabling integration of multi-modal sensor signal generation techniques into a single device. Such integration has the potential to make diagnostic tools more efficient, highly ...
Mar. 29, 2016
ScienceMedicine & Diagnostics
Modelling the Growth and Treatment of Tumours
Cancer is a leading cause of morbidity and mortality worldwide, with approximately 14 million new cases and 8.2 million cancer related deaths in 2012 [1]. Moreover, the global cancer burden is expected to exceed 20 million new cancer cases ...
Mar. 15, 2016
ScienceMedicine & Diagnostics
Bacteria against Cancer
Cancer, a diagnosis that still hits patients very hard. Despite intensive research as well as newly developed improved therapies, cancer remains the second most frequent cause of death in industrialized countries. Increased life expectancy ...
Feb. 19, 2016
ScienceMedicine & Diagnostics
Photonic devices for future chip-integrated biosensors
On-chip integrated photonic biosensors can lead to major advances in medical diagnostics, food and environmental monitoring through the rapid, and precise analysis of various substances. This offers the prospect of a cost effective ...

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