Science Overview | Laboratory Journal – Business Web for Users in Science and Industry

Jul. 23, 2010
ScienceMedicine & Diagnostics
Fostering MALDI Imaging MS for Clinical Investigations
FFPE Stored SamplesTissues coming from surgery have been long collected and stored under formalin-fixed paraffin-embedded (FFPE) form. Nowadays, the existence of this huge and easily accessible library of clinically relevant samples, leads ...
Jul. 23, 2010
ScienceInformation Technology (IT)
Towards High-density Non-volatile Solid State Memories
We want the electronic gadgets of tomorrow to be smaller and lighter, but also faster and more powerful: Whether MP3 players, camera mobile phones, navigation systems or notebooks, all have to be compact but also able to store increasingly ...
Jul. 23, 2010
ScienceEnvironment
Siliceous Sponge Reefs
Siliceous sponge reefs occur several times in Earth history. In the late Jurassic this facies was widespread mainly on the northern shelf of the Tethys. After this time there was a drastic reduction in the occurrence of these reefs and it ...
Jul. 23, 2010
ScienceFood
Data Analysis Strategies in Nutritional Metabolomics
In the expanding field of nutritional metabolomics the use of optimized and robust strategies are essential to find meaningful and significant results. Data from nutritional studies can be extremely large, multidimensional and complex. ...
Jul. 23, 2010
ScienceMedicine & Diagnostics
Developing MALDI Imaging Technology for Cancer Profile
Normal and diseased tissues are complex mixtures of different cell populations. A better understanding of protein expression changes that occur during diseases needs sensitive and specific technologies for each of these cell types. Mass ...
Jul. 23, 2010
SciencePharma & Drug Discovery
The Good, the Bad and the Very Bad
Interest in cancer stem cells (CSC) continues to grow and we are now at a stage where a fundamental understanding of their mechanism of development and disease progression can be addressed [1]. Observations that solid tumors are typically ...
Jul. 23, 2010
ScienceEnvironment
Washing or Throwing?
Cleaning problems can have various consequences leading to contamination of drugs with a risk for the patients but also for the staff of the company. Further, contaminated equipment can cause ecological problems like environmental ...
Jul. 23, 2010
SciencePharma & Drug Discovery
DNA-Encoded Chemical Libraries
The isolation of specific binding molecules is a central problem in the drug discovery process. Libraries of organic molecules, covalently coupled to DNA tags that serve as amplifiable identification bar codes, represent a new tool for the ...

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