Apr. 14, 2015
Webcast

Bioessays: Adaptation of Influenza Virus

to Gallinaceous Poultry May Limit its Pandemic Potential

Bioessays video called 'Influenza virus' adaptation to gallinaceous poultry may limit its pandemic potential' by Jason Long, Camilla Benfield and Wendy Barclay is about the adaptation of influenza viruses to poultry results in altered receptor binding, increased pH of fusion of the haemagglutinin and neuraminidase stalk deletions, which may compromise human to-human transmission. In a "Problems & Paradigms" article, Jason Long, Camilla Benfield and Wendy Barclay suggest a trade-off exists between high pathogenicity and transmissibility since HA stability may confer greater susceptibility to control by IFITM-3.

Original publication:
Long J.S. et al.: One-way trip: Influenza virus' adaptation to gallinaceous poultry may limit its pandemic potential. Bioessays, 37 (2015): 204-212. doi: 10.1002/bies.201400133

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